Progressive Care Nursing Certification (PCCN) Practice Exam

In the presence of DIC, what happens to fibrinogen levels?

1. They increase

2. They decrease

3. They remain normal

4. They fluctuate significantly

The correct answer is: They decrease

In the presence of disseminated intravascular coagulation (DIC), fibrinogen levels typically decrease. DIC is a complex disorder characterized by the excessive activation of the coagulation cascade, leading to widespread clot formation throughout the small vessels. As fibrinogen is consumed in the formation of fibrin clots, its levels decrease significantly. In DIC, there is also an increase in fibrin degradation products as clots are broken down, which further contributes to the decrease in fibrinogen. Monitoring fibrinogen levels is crucial in patients suspected of having DIC, as a low level can indicate ongoing coagulation activity and the severity of the condition. Therefore, the decrease in fibrinogen levels serves as an important indicator of the presence of DIC and its effects on the hemostatic balance in the body.